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Did you mean csa and breast neoplasms (127 results)?
Interplay of ERalpha binding and DNA methylation in the intron-2 determines the expression and estrogen regulation of cystatin A in breast cancer cells.
John Mary DJS, Sikarwar G, Kumar A, Limaye AM. John Mary DJS, et al. Mol Cell Endocrinol. 2020 Mar 15;504:110701. doi: 10.1016/j.mce.2020.110701. Epub 2020 Jan 8. Mol Cell Endocrinol. 2020. PMID: 31926189
Despite advances in early detection and treatment, invasion and metastasis of breast tumors remains a major hurdle. Cystatin A (CSTA, also called stefin A), an estrogen-regulated gene in breast cancer cells, is an inhibitor of cysteine cathepsins, and a purpo …
Despite advances in early detection and treatment, invasion and metastasis of breast tumors remains a major hurdle. Cystatin A (CS …
Stefins and lysosomal cathepsins B, L and D in human breast carcinoma.
Lah TT, Kokalj-Kunovar M, Strukelj B, Pungercar J, Barlic-Maganja D, Drobnic-Kosorok M, Kastelic L, Babnik J, Golouh R, Turk V. Lah TT, et al. Int J Cancer. 1992 Jan 2;50(1):36-44. doi: 10.1002/ijc.2910500109. Int J Cancer. 1992. PMID: 1728611
In the study of 50 matched pairs of breast carcinoma and normal breast tissue, the activities of cysteine proteinases (CPs), cathepsin (Cat) B and Cat L in tumors were increased on average by 18.5-fold and 52.5-fold respectively. ...A 2-year follow-up study showed a …
In the study of 50 matched pairs of breast carcinoma and normal breast tissue, the activities of cysteine proteinases (CPs), c …
Comparison of potential biological markers cathepsin B, cathepsin L, stefin A and stefin B with urokinase and plasminogen activator inhibitor-1 and clinicopathological data of breast carcinoma patients.
Levicar N, Kos J, Blejec A, Golouh R, Vrhovec I, Frkovic-Grazio S, Lah TT. Levicar N, et al. Cancer Detect Prev. 2002;26(1):42-9. doi: 10.1016/s0361-090x(02)00015-6. Cancer Detect Prev. 2002. PMID: 12088202
The aim of the study was to compare the expression of new potential biological tumor markers, the lysosomal cysteine proteinases and their endogenous inhibitors, with that of the serine proteinases and their inhibitors in breast cancinoma and to relate their levels to the …
The aim of the study was to compare the expression of new potential biological tumor markers, the lysosomal cysteine proteinases and their e …
Cystatins and cathepsins in breast carcinoma.
Lah TT, Kokalj-Kunovar M, Drobnic-Kosorok M, Babnik J, Golouh R, Vrhovec I, Turk V. Lah TT, et al. Biol Chem Hoppe Seyler. 1992 Jul;373(7):595-604. doi: 10.1515/bchm3.1992.373.2.595. Biol Chem Hoppe Seyler. 1992. PMID: 1515089
Abnormal intracellular distribution, increased activities and secretion of cysteine proteinases (CPs) cathepsin B (Cat B) and L (Cat L), were associated with tumor progression. In the present study of matched pairs of breast carcinoma and normal breast tissue, the a …
Abnormal intracellular distribution, increased activities and secretion of cysteine proteinases (CPs) cathepsin B (Cat B) and L (Cat L), wer …
Expression of cysteine peptidase cathepsin L and its inhibitors stefins A and B in relation to tumorigenicity of breast cancer cell lines.
Zajc I, Sever N, Bervar A, Lah TT. Zajc I, et al. Cancer Lett. 2002 Dec 10;187(1-2):185-90. doi: 10.1016/s0304-3835(02)00452-4. Cancer Lett. 2002. PMID: 12359367
The in vitro invasiveness of human breast cancer cell lines was compared with their reported tumorigenicity in vivo, increasing from MCF7, MDA-MB468, MDA-MB231 to MDA-MB435 cells. ...
The in vitro invasiveness of human breast cancer cell lines was compared with their reported tumorigenicity in vivo, increasing from …
Estrogen regulation in human breast cancer cells of new downstream gene targets involved in estrogen metabolism, cell proliferation and cell transformation.
Vendrell JA, Magnino F, Danis E, Duchesne MJ, Pinloche S, Pons M, Birnbaum D, Nguyen C, Theillet C, Cohen PA. Vendrell JA, et al. J Mol Endocrinol. 2004 Apr;32(2):397-414. doi: 10.1677/jme.0.0320397. J Mol Endocrinol. 2004. PMID: 15072547
We explored, by cDNA mini-arrays, gene expression measurements of MVLN, a human breast carcinoma cell line derived from MCF-7, after 4 days of exposure to 17beta-estradiol (E(2)) treatment, in order to extend our understanding of the mechanism of the pharmacological action …
We explored, by cDNA mini-arrays, gene expression measurements of MVLN, a human breast carcinoma cell line derived from MCF-7, after …
Myoepithelial cell-specific expression of stefin A as a suppressor of early breast cancer invasion.
Duivenvoorden HM, Rautela J, Edgington-Mitchell LE, Spurling A, Greening DW, Nowell CJ, Molloy TJ, Robbins E, Brockwell NK, Lee CS, Chen M, Holliday A, Selinger CI, Hu M, Britt KL, Stroud DA, Bogyo M, Möller A, Polyak K, Sloane BF, O'Toole SA, Parker BS. Duivenvoorden HM, et al. J Pathol. 2017 Dec;243(4):496-509. doi: 10.1002/path.4990. Epub 2017 Oct 31. J Pathol. 2017. PMID: 29086922
Using the MMTV-PyMT breast cancer model and pharmacological protease inhibitors, we reveal that cysteine cathepsins have important roles in early-stage tumorigenesis. ...Importantly, we confirmed that stefin A was indeed abundant in myoepithelial cells in breast tis …
Using the MMTV-PyMT breast cancer model and pharmacological protease inhibitors, we reveal that cysteine cathepsins have important ro …
Prognostic significance of cysteine proteinases cathepsins B and L and their endogenous inhibitors stefins A and B in patients with squamous cell carcinoma of the head and neck.
Strojan P, Budihna M, Smid L, Svetic B, Vrhovec I, Kos J, Skrk J. Strojan P, et al. Clin Cancer Res. 2000 Mar;6(3):1052-62. Clin Cancer Res. 2000. PMID: 10741734
They were identified as potential prognosticators in various malignant diseases, particularly in breast cancer. The aim of the present study was to determine the concentrations of Cats B and L and Stefs A and B in the tumor and adjacent normal tissue samples collected from …
They were identified as potential prognosticators in various malignant diseases, particularly in breast cancer. The aim of the presen …
PPAR signaling pathway may be an important predictor of breast cancer response to neoadjuvant chemotherapy.
Chen YZ, Xue JY, Chen CM, Yang BL, Xu QH, Wu F, Liu F, Ye X, Meng X, Liu GY, Shen ZZ, Shao ZM, Wu J. Chen YZ, et al. Cancer Chemother Pharmacol. 2012 Nov;70(5):637-44. doi: 10.1007/s00280-012-1949-0. Epub 2012 Aug 19. Cancer Chemother Pharmacol. 2012. PMID: 22903535 Clinical Trial.
PURPOSE: Neoadjuvant chemotherapy for advanced breast cancer may improve the radicality for a subset of patients, but others may suffer from severe adverse drug reactions without any benefit. ...METHODS: A total of 61 patients with stage II-III breast cancer were in …
PURPOSE: Neoadjuvant chemotherapy for advanced breast cancer may improve the radicality for a subset of patients, but others may suff …
Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer.
Lee S, Stewart S, Nagtegaal I, Luo J, Wu Y, Colditz G, Medina D, Allred DC. Lee S, et al. Cancer Res. 2012 Sep 1;72(17):4574-86. doi: 10.1158/0008-5472.CAN-12-0636. Epub 2012 Jul 2. Cancer Res. 2012. PMID: 22751464 Free PMC article.
Molecular mechanisms mediating the progression of ductal carcinoma in situ (DCIS) to invasive breast cancer remain largely unknown. We used gene expression profiling of human DCIS (n = 53) and invasive breast cancer (n = 51) to discover uniquely expressed genes that …
Molecular mechanisms mediating the progression of ductal carcinoma in situ (DCIS) to invasive breast cancer remain largely unknown. W …
11 results